T. Rowe PriceHealthTDNA · Nasdaq

T. Rowe Price Biotech ETF (TDNA)

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Price: $24.77; —12 Nov 2026
Assets: $10M; Total net assets
Expense ratio: 0.55%; Category 1.00%
Yield: —; Trailing distributions

1Y return: —; Category 23.8%
3Y CAGR: —; Category 20.2%
5Y CAGR: —; Category 3.9%

$24.77—12 Nov 2026

Fund

Assets: $10M
Expense: 0.55%
Categ. exp: 1.00%
Yield: —

ReturnFundCateg.

1Y—23.8%

3Y—20.2%

5Y—3.9%

Launch-2.8%—

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T. Rowe Price Biotech ETF

Calendar-year returns

Fund only: no comparison series covers this fund's history.

Risk statistics

Five years of daily closes. Risk-free rate 4% a year.

Standard deviation: —
Maximum drawdown: —
Sharpe ratio: —
Sortino ratio: —
Beta: —
Alpha: —
R²: —
Information ratio: —
Upside capture: —
Downside capture: —
Tracking error: —

Trailing returns compared with benchmark
Period	1M	3M	6M	YTD	1Y	3YCAGR	5YCAGR	10YCAGR	LaunchCAGR
ETF	+7.4%	—	—	—	—	—	—	—	-2.8%
Health average	6.4%	4.0%	21.1%	20.0%	23.8%	20.2%	3.9%	10.1%	11.2%
Difference	+0.9%	—	—	—	—	—	—	—	-14.0%

Holdings

The 10 largest positions make up 27.8% of the fund.

Top holdings

Largest holdings by weight
Ticker	Holding	Weight
ARGX	argenx SE ADR	5.50%
KYMR	Kymera Therapeutics Inc Ordinary Shares	4.01%
INSM	Insmed Inc	2.64%
KOD	Kodiak Sciences Inc	2.58%
NTRA	Natera Inc	2.43%
RVMD	Revolution Medicines Inc Ordinary Shares	2.37%
VRTX	Vertex Pharmaceuticals Inc	2.28%
ALNY	Alnylam Pharmaceuticals Inc	2.04%
MRNA	Moderna Inc	2.02%
UTHR	United Therapeutics Corp	1.96%

Portfolio valuation

Weighted averages of what the fund holds.

P/E: —
P/B: 6.0
P/S: 13.1
P/CF: —

Sector allocation

Share of the equity the fund holds.

Health care100.0%

Asset mix

Stocks98.7%
Other1.3%

ETF details

Issuer: T. Rowe Price
Category: Equity · Health
Ticker: TDNA
Exchange: Nasdaq
Inception: 16 Sept 2026 (0.2 years)
Structure: Exchange Traded Fund
Expense ratio: 0.55% (category 1.00%)
Holdings turnover: 0% (category 51%)
Distribution yield: —
Beta, 3 years: 0.00
Total net assets: $10M

Prices and returns as of 12 Nov 2026; total return with distributions reinvested, before brokerage and taxes. Not investment advice.

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