iSharesHealthIBRN · NYSE Arca

iShares Neuroscience and Healthcare ETF (IBRN)

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Price: $34.34; —12 Nov 2026
Assets: $6.6M; Total net assets
Expense ratio: 0.47%; Category 1.00%
Yield: 0.97%; Trailing distributions

1Y return: 18.7%-5.2%; Category 23.8%
3Y CAGR: 20.8%+0.5%; Category 20.2%
5Y CAGR: —; Category 3.9%

$34.34—12 Nov 2026

Fund

Assets: $6.6M
Expense: 0.47%
Categ. exp: 1.00%
Yield: 0.97%

ReturnFundCateg.

1Y18.7%23.8%

3Y20.8%20.2%

5Y—3.9%

Launch8.9%—

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iShares Neuroscience and Healthcare ETF

Calendar-year returns

Fund only: no comparison series covers this fund's history.

Risk statistics

Five years of daily closes. Risk-free rate 4% a year.

Standard deviation: —
Maximum drawdown: —
Sharpe ratio: —
Sortino ratio: —
Beta: —
Alpha: —
R²: —
Information ratio: —
Upside capture: —
Downside capture: —
Tracking error: —

Trailing returns compared with benchmark
Period	1M	3M	6M	YTD	1Y	3YCAGR	5YCAGR	10YCAGR	LaunchCAGR
ETF	+13.4%	-12.2%	-4.0%	+6.3%	+18.7%	+20.8%	—	—	+8.9%
Health average	6.4%	4.0%	21.1%	20.0%	23.8%	20.2%	3.9%	10.1%	11.2%
Difference	+6.9%	-16.1%	-25.0%	-13.7%	-5.2%	+0.5%	—	—	-2.3%

Holdings

The 10 largest positions make up 41.1% of the fund.

Top holdings

Largest holdings by weight
Ticker	Holding	Weight
BIIB	Biogen Inc	4.74%
EWTX	Edgewise Therapeutics Inc	4.36%
PTCT	PTC Therapeutics Inc	4.33%
ARGX	argenx SE ADR	4.31%
NBIX	Neurocrine Biosciences Inc	4.22%
ALKS	Alkermes PLC	4.07%
SRRK	Scholar Rock Holding Corp	4.04%
PRAX	Praxis Precision Medicines Inc Ordinary Shares	3.83%
DNTH	Dianthus Therapeutics Inc	3.77%
SUPN	Supernus Pharmaceuticals Inc	3.43%

Portfolio valuation

Weighted averages of what the fund holds.

P/E: —
P/B: 3.6
P/S: 4.2
P/CF: —

Sector allocation

Share of the equity the fund holds.

Health care100.0%

Asset mix

Stocks99.9%
Cash0.1%

ETF details

Issuer: iShares
Category: Equity · Health
Ticker: IBRN
Exchange: NYSE Arca
Inception: 24 Aug 2022 (4.2 years)
Structure: Exchange Traded Fund
Expense ratio: 0.47% (category 1.00%)
Holdings turnover: 52% (category 51%)
Distribution yield: 0.97%
Beta, 3 years: 0.82
Total net assets: $6.6M

Prices and returns as of 12 Nov 2026; total return with distributions reinvested, before brokerage and taxes. Not investment advice.

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