Franklin Templeton, IncHealthHELX · Cboe BZX

Franklin Genomic Advancements ETF (HELX)

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Price: $42.96; —12 Nov 2026
Assets: $36.2M; Total net assets
Expense ratio: 0.50%; Category 1.00%
Yield: 0.32%; Trailing distributions

1Y return: 21.6%-2.2%; Category 23.8%
3Y CAGR: 18.0%-2.2%; Category 20.2%
5Y CAGR: -3.0%-6.9%; Category 3.9%

$42.96—12 Nov 2026

Fund

Assets: $36.2M
Expense: 0.50%
Categ. exp: 1.00%
Yield: 0.32%

ReturnFundCateg.

1Y21.6%23.8%

3Y18.0%20.2%

5Y-3.0%3.9%

Launch9.2%—

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Franklin Genomic Advancements ETF

Calendar-year returns

Fund only: no comparison series covers this fund's history.

Risk statistics

Five years of daily closes. Risk-free rate 4% a year.

Standard deviation: —
Maximum drawdown: —
Sharpe ratio: —
Sortino ratio: —
Beta: —
Alpha: —
R²: —
Information ratio: —
Upside capture: —
Downside capture: —
Tracking error: —

Trailing returns compared with benchmark
Period	1M	3M	6M	YTD	1Y	3YCAGR	5YCAGR	10YCAGR	LaunchCAGR
ETF	+3.1%	+5.4%	+27.5%	+18.3%	+21.6%	+18.0%	-3.0%	—	+9.2%
Health average	6.4%	4.0%	21.1%	20.0%	23.8%	20.2%	3.9%	10.1%	11.2%
Difference	-3.4%	+1.4%	+6.5%	-1.7%	-2.2%	-2.2%	-6.9%	—	-2.0%

Holdings

The 10 largest positions make up 50.2% of the fund.

Top holdings

Largest holdings by weight
Ticker	Holding	Weight
NTRA	Natera Inc	10.19%
GH	Guardant Health Inc	9.69%
TWST	Twist Bioscience Corp	5.25%
KRYS	Krystal Biotech Inc	5.08%
ADPT	Adaptive Biotechnologies Corp	4.82%
LGND	Ligand Pharmaceuticals Inc	4.46%
BBIO	BridgeBio Pharma Inc	2.77%
TVTX	Travere Therapeutics Inc Ordinary Shares	2.67%
MEDP	Medpace Holdings Inc	2.65%
VRTX	Vertex Pharmaceuticals Inc	2.59%

Portfolio valuation

Weighted averages of what the fund holds.

P/E: —
P/B: 6.6
P/S: 10.2
P/CF: 27.7

Sector allocation

Share of the equity the fund holds.

Health care97.0%
Materials2.3%
Technology0.7%

Asset mix

Stocks99.9%
Cash0.1%

ETF details

Issuer: Franklin Templeton, Inc
Category: Equity · Health
Ticker: HELX
Exchange: Cboe BZX
Inception: 25 Feb 2020 (6.7 years)
Structure: Exchange Traded Fund
Expense ratio: 0.50% (category 1.00%)
Holdings turnover: 29% (category 51%)
Distribution yield: 0.32%
Beta, 3 years: 0.82
Total net assets: $36.2M

Prices and returns as of 12 Nov 2026; total return with distributions reinvested, before brokerage and taxes. Not investment advice.

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