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State Street Investment ManagementHealthXBI · NYSE Arca

State Street SPDR S&P Biotech ETF (XBI)

Price
$155.98
—30 Oct 2026
Assets
$10.4B
Total net assets
Expense ratio
0.35%
Category 1.00%
Yield
0.35%
Trailing distributions
3Y CAGR
34.0%+12.5%
Category 21.5%
5Y CAGR
4.7%+0.6%
Category 4.1%
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State Street SPDR S&P Biotech ETF

Calendar-year returns

Fund only: no comparison series covers this fund's history.

Risk statistics

Five years of daily closes. Risk-free rate 4% a year.

Standard deviation
—
Maximum drawdown
—
Sharpe ratio
—
Sortino ratio
—
Beta
—
Alpha
—
R²
—
Information ratio
—
Upside capture
—
Downside capture
—
Tracking error
—
Trailing returns compared with benchmark
Period1M3M6MYTD1Y3YCAGR5YCAGR10YCAGRLaunchCAGR
ETF-1.1%+6.1%+19.7%+28.1%+40.0%+34.0%+4.7%+10.8%+11.8%
Health average3.6%9.9%23.0%20.4%28.8%21.5%4.1%10.8%11.6%
Difference-4.7%-3.8%-3.3%+7.6%+11.2%+12.5%+0.6%0.0%+0.1%

Holdings

The 10 largest positions make up 16.7% of the fund.

Top holdings

Largest holdings by weight
TickerHoldingWeight
TWSTTwist Bioscience Corp2.21%
MRNAModerna Inc2.04%
NTRANatera Inc1.80%
IOVAIovance Biotherapeutics Inc1.62%
AMGNAmgen Inc1.55%
BIIBBiogen Inc1.54%
UTHRUnited Therapeutics Corp1.54%
ABBVAbbVie Inc1.50%
HALOHalozyme Therapeutics Inc1.48%
SYRESpyre Therapeutics Inc1.47%

Portfolio valuation

Weighted averages of what the fund holds.

P/E
—
P/B
4.9
P/S
8.1
P/CF
—

Sector allocation

Share of the equity the fund holds.

2sectors
  1. Health care99.3%
  2. Financial services0.7%

Asset mix

  • Stocks100.0%
  • Cash0.0%

ETF details

Issuer
State Street Investment Management
Category
Equity · Health
Ticker
XBI
Exchange
NYSE Arca
Inception
31 Jan 2006 (20.7 years)
Structure
Exchange Traded Fund
Expense ratio
0.35% (category 1.00%)
Holdings turnover
71% (category 51%)
Distribution yield
0.35%
Beta, 3 years
1.09
Total net assets
$10.4B

Prices and returns as of 30 Oct 2026; total return with distributions reinvested, before brokerage and taxes. Not investment advice.

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