ALPSHealthSBIO · NYSE Arca
ALPS Medical Breakthroughs ETF (SBIO)
- Price
- $63.29
- —11 Sept 2026
- Assets
- $240M
- Total net assets
- Expense ratio
- 0.50%
- Category 1.00%
- Yield
- 0.00%
- Trailing distributions
- 3Y CAGR
- 30.0%+16.5%
- Category 13.5%
- 5Y CAGR
- 7.3%+5.4%
- Category 1.9%
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ALPS Medical Breakthroughs ETF
Calendar-year returns
Fund only: no comparison series covers this fund's history.
Risk statistics
Five years of daily closes. Risk-free rate 4% a year.
- Standard deviation
- —
- Maximum drawdown
- —
- Sharpe ratio
- —
- Sortino ratio
- —
- Beta
- —
- Alpha
- —
- R²
- —
- Information ratio
- —
- Upside capture
- —
- Downside capture
- —
- Tracking error
- —
Holdings
The 10 largest positions make up 31.4% of the fund.
Top holdings
| Ticker | Holding | Weight |
|---|---|---|
| CRNX | Crinetics Pharmaceuticals Inc | 4.60% |
| APGE | Apogee Therapeutics Inc | 4.30% |
| CGON | CG Oncology Inc | 3.41% |
| TVTX | Travere Therapeutics Inc Ordinary Shares | 3.17% |
| XENE | Xenon Pharmaceuticals Inc | 2.99% |
| DNTH | Dianthus Therapeutics Inc | 2.96% |
| ORKA | Oruka Therapeutics Inc | 2.87% |
| ACAD | ACADIA Pharmaceuticals Inc | 2.54% |
| EWTX | Edgewise Therapeutics Inc | 2.31% |
| DFTX | Definium Therapeutics Inc Ordinary Shares | 2.23% |
Portfolio valuation
Weighted averages of what the fund holds.
- P/E
- —
- P/B
- 4.0
- P/S
- 8.3
- P/CF
- —
Sector allocation
Share of the equity the fund holds.
- Health care100.0%
Asset mix
- Stocks100.0%
ETF details
- Issuer
- ALPS
- Category
- Equity · Health
- Ticker
- SBIO
- Exchange
- NYSE Arca
- Inception
- 30 Dec 2014 (11.7 years)
- Structure
- Exchange Traded Fund
- Expense ratio
- 0.50% (category 1.00%)
- Holdings turnover
- 58% (category 51%)
- Distribution yield
- 0.00%
- Beta, 3 years
- 0.92
- Total net assets
- $240M
Prices and returns as of 11 Sept 2026; total return with distributions reinvested, before brokerage and taxes. Not investment advice.
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